Detalhe da pesquisa
1.
Tumor acidosis-induced DNA damage response and tetraploidy enhance sensitivity to ATM and ATR inhibitors.
EMBO Rep
; 25(3): 1469-1489, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366255
2.
Metabolic adaptation towards glycolysis supports resistance to neoadjuvant chemotherapy in early triple negative breast cancers.
Breast Cancer Res
; 26(1): 29, 2024 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38374113
3.
Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators.
Biochem J
; 479(12): 1317-1336, 2022 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670459
4.
Microenvironment-driven intratumoral heterogeneity in head and neck cancers: clinical challenges and opportunities for precision medicine.
Drug Resist Updat
; 60: 100806, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121337
5.
Reconciling environment-mediated metabolic heterogeneity with the oncogene-driven cancer paradigm in precision oncology.
Semin Cell Dev Biol
; 98: 202-210, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31103464
6.
Impact of cancer metabolism on therapy resistance - Clinical implications.
Drug Resist Updat
; 59: 100797, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34955385
7.
Acetate: Friend or foe against breast tumour growth in the context of obesity?
J Cell Mol Med
; 24(24): 14195-14204, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33107196
8.
Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling.
Biochim Biophys Acta Rev Cancer
; 1868(1): 7-15, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28110019
9.
Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia.
Biochem J
; 476(24): 3687-3704, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31782497
10.
Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells.
Int J Mol Sci
; 21(24)2020 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33316932
11.
The NLRP3 Inflammasome Has a Critical Role in Peritoneal Dialysis-Related Peritonitis.
J Am Soc Nephrol
; 28(7): 2038-2052, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193826
12.
Emerging roles of lipid metabolism in cancer progression.
Curr Opin Clin Nutr Metab Care
; 20(4): 254-260, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28403011
13.
Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
Curr Opin Clin Nutr Metab Care
; 18(4): 346-53, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26001655
14.
Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein.
J Biol Chem
; 287(3): 1923-31, 2012 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22128158
15.
Repurposing Sulfasalazine as a Radiosensitizer in Hypoxic Human Colorectal Cancer.
Cancers (Basel)
; 15(8)2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37190291
16.
Establishment of head and neck squamous cell carcinoma mouse models for cetuximab resistance and sensitivity.
Cancer Drug Resist
; 6(4): 709-728, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38239393
17.
Discovery of Mitochondrial Complex I Inhibitors as Anticancer and Radiosensitizer Drugs Based on Compensatory Stimulation of Lactate Release.
Cancers (Basel)
; 14(21)2022 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36358872
18.
Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification.
Metabolites
; 12(6)2022 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35736489
19.
Targeting cancer cells in acidosis with conjugates between the carnitine palmitoyltransferase 1 inhibitor etomoxir and pH (low) insertion peptides.
Int J Pharm
; 624: 122041, 2022 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35868479
20.
Tumor Metabolism Is Affected by Obesity in Preclinical Models of Triple-Negative Breast Cancer.
Cancers (Basel)
; 14(3)2022 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35158830